| ncRNA Symbol: | PPP1R13B |
| Full Name: | protein phosphatase 1 regulatory subunit 13B |
| Category: | mRNA |
| Synonyms: | ASPP1|p53BP2-like|p85 |
| Chromosome: | chr14 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 103733752 | End Site(bp): | 103847590 | |
| Gene Summary: | This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008] |
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