ctcRbase

Entry Detail

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General Information

Database ID: SKCM08540 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PPP2R5A Full Name: protein phosphatase 2 regulatory subunit B'alpha Category: mRNA Synonyms: B56A|B56alpha|PR61A Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 212285537 End Site(bp): 212361863 Gene Summary: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000066027 HGNC ID: HGNC:9309 Entrez Gene: 5525

Expression Profile of PPP2R5A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1297 YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-299-5p YES NO YES hsa-miR-300 YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-455-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-613 YES YES YES Display: