| ncRNA Symbol: | SMG6 |
| Full Name: | SMG6, nonsense mediated mRNA decay factor |
| Category: | mRNA |
| Synonyms: | C17orf31|EST1A|SMG-6|hSMG5/7a |
| Chromosome: | chr17 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 2059839 | End Site(bp): | 2303771 |
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| Gene Summary: | This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014] |
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