ctcRbase

Entry Detail

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General Information

Database ID: SKCM08572 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NRXN3 Full Name: neurexin 3 Category: mRNA Synonyms: C14orf60 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 78170373 End Site(bp): 79868290 Gene Summary: This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012] External Links: Ensembl ID: ENSG00000021645 HGNC ID: HGNC:8010 Entrez Gene: 9369

Expression Profile of NRXN3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-147a YES NO NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES YES hsa-miR-190b YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-362-5p YES NO YES hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-431-5p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES NO YES hsa-miR-582-5p YES NO YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: