ctcRbase

Entry Detail

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General Information

Database ID: SKCM08597 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ESRRA Full Name: estrogen related receptor alpha Category: mRNA Synonyms: ERR1|ERRa|ERRalpha|ESRL1|NR3B1 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 64305572 End Site(bp): 64316743 Gene Summary: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] External Links: Ensembl ID: ENSG00000173153 HGNC ID: HGNC:3471 Entrez Gene: 2101

Expression Profile of ESRRA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-137 YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-324-5p YES YES NO hsa-miR-326 YES NO YES hsa-miR-330-5p YES NO YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-365a-3p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-760 YES NO YES Display: