| ncRNA Symbol: | PIGW |
| Full Name: | phosphatidylinositol glycan anchor biosynthesis class W |
| Category: | mRNA |
| Synonyms: | Gwt1|HPMRS5 |
| Chromosome: | chr17 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 36535020 | End Site(bp): | 36539310 | |
| Gene Summary: | The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017] |
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