Entry Detail



General Information

Database ID:SKCM08620
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NCK2
Full Name:NCK adaptor protein 2
Category:mRNA
Synonyms:GRB4|NCKbeta
Chromosome:chr2
Strand:+
Coordinate:
Start Site(bp):105744897End Site(bp):105894274
Gene Summary:This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000071051
HGNC ID:HGNC:7665
Entrez Gene:8440



Expression Profile of NCK2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-125a-5p
YES
YES
NO
hsa-miR-125b-5p
YES
YES
NO
hsa-miR-137
YES
YES
NO
hsa-miR-138-5p
YES
YES
NO
hsa-miR-139-5p
YES
YES
NO
hsa-miR-1-3p
YES
NO
YES
hsa-miR-142-3p
YES
YES
YES
hsa-miR-147a
YES
NO
NO
hsa-miR-183-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-206
YES
YES
YES
hsa-miR-222-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-31-5p
YES
YES
YES
hsa-miR-339-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-411-5p
YES
YES
NO
hsa-miR-455-5p
YES
YES
YES
hsa-miR-486-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-505-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-613
YES
YES
YES
hsa-miR-758-3p
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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