Entry Detail



General Information

Database ID:SKCM08623
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:AKAP1
Full Name:A-kinase anchoring protein 1
Category:mRNA
Synonyms:AKAP|AKAP121|AKAP149|AKAP84|D-AKAP1|PPP1R43|PRKA1|SAKAP84|TDRD17
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):57085092End Site(bp):57121349
Gene Summary:The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000121057
HGNC ID:HGNC:367
Entrez Gene:8165



Expression Profile of AKAP1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-125a-5p
YES
NO
YES
hsa-miR-125b-5p
YES
NO
YES
hsa-miR-130a-3p
YES
YES
YES
hsa-miR-130b-3p
YES
YES
YES
hsa-miR-139-5p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-145-5p
YES
YES
NO
hsa-miR-148a-3p
YES
YES
YES
hsa-miR-148b-3p
YES
YES
YES
hsa-miR-152-3p
YES
YES
YES
hsa-miR-186-5p
YES
YES
YES
hsa-miR-199a-5p
YES
YES
YES
hsa-miR-199b-5p
YES
YES
YES
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-204-5p
YES
YES
YES
hsa-miR-211-5p
YES
YES
YES
hsa-miR-223-3p
YES
YES
YES
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
YES
hsa-miR-301b-3p
YES
YES
YES
hsa-miR-329-3p
YES
YES
YES
hsa-miR-362-3p
YES
YES
YES
hsa-miR-375
YES
NO
YES
hsa-miR-409-5p
YES
NO
YES
hsa-miR-421
YES
YES
YES
hsa-miR-431-5p
YES
YES
YES
hsa-miR-450a-5p
YES
YES
NO
hsa-miR-454-3p
YES
YES
YES
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