ctcRbase

Entry Detail

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General Information

Database ID: SKCM08633 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SMPD4 Full Name: sphingomyelin phosphodiesterase 4 Category: mRNA Synonyms: NET13|NSMASE-3|NSMASE3|SKNY Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 130151392 End Site(bp): 130182750 Gene Summary: The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017] External Links: Ensembl ID: ENSG00000136699 HGNC ID: HGNC:32949 Entrez Gene: 55627

Expression Profile of SMPD4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-9-5p YES NO YES Display: