Entry Detail



General Information

Database ID:SKCM09103
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ID2
Full Name:inhibitor of DNA binding 2
Category:mRNA
Synonyms:GIG8|ID2A|ID2H|bHLHb26
Chromosome:chr2
Strand:+
Coordinate:
Start Site(bp):8678845End Site(bp):8684453
Gene Summary:The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]
External Links:
Ensembl ID:ENSG00000115738
HGNC ID:HGNC:5361
Entrez Gene:3398



Expression Profile of ID2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-142-5p
YES
NO
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-300
YES
YES
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-330-3p
YES
NO
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
YES
hsa-miR-429
YES
YES
NO
hsa-miR-455-3p
YES
NO
YES
hsa-miR-599
YES
YES
NO
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