Entry Detail



General Information

Database ID:SKCM09138
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:IL27RA
Full Name:interleukin 27 receptor subunit alpha
Category:mRNA
Synonyms:CRL1|IL-27RA|IL27R|TCCR|WSX1|zcytor1
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):14031748End Site(bp):14053216
Gene Summary:In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000104998
HGNC ID:HGNC:17290
Entrez Gene:9466



Expression Profile of IL27RA Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-140-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-431-5p
YES
YES
NO
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