ctcRbase

Entry Detail

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General Information

Database ID: SKCM09143 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RPS6KA1 Full Name: ribosomal protein S6 kinase A1 Category: mRNA Synonyms: HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 26529761 End Site(bp): 26575030 Gene Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000117676 HGNC ID: HGNC:10430 Entrez Gene: 6195

Expression Profile of RPS6KA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-708-5p YES YES NO hsa-miR-93-5p YES YES YES Display: