ctcRbase

Entry Detail

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General Information

Database ID: SKCM09172 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: STK36 Full Name: serine/threonine kinase 36 Category: mRNA Synonyms: FU Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 218672026 End Site(bp): 218702716 Gene Summary: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000163482 HGNC ID: HGNC:17209 Entrez Gene: 27148

Expression Profile of STK36 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-370-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-613 YES YES NO Display: