ctcRbase

Entry Detail

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General Information

Database ID: SKCM09176 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RARB Full Name: retinoic acid receptor beta Category: mRNA Synonyms: HAP|MCOPS12|NR1B2|RARbeta1|RRB2 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 25174332 End Site(bp): 25597932 Gene Summary: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014] External Links: Ensembl ID: ENSG00000077092 HGNC ID: HGNC:9865 Entrez Gene: 5915

Expression Profile of RARB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES YES YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-454-3p YES NO YES hsa-miR-455-3p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-93-5p YES YES YES Display: