ctcRbase

Entry Detail

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General Information

Database ID: SKCM09210 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BAK1 Full Name: BCL2 antagonist/killer 1 Category: mRNA Synonyms: BAK|BAK-LIKE|BCL2L7|CDN1 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 33572547 End Site(bp): 33580293 Gene Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000030110 HGNC ID: HGNC:949 Entrez Gene: 578

Expression Profile of BAK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-384 YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-451a YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: