ctcRbase

Entry Detail

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General Information

Database ID: SKCM09253 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SUFU Full Name: SUFU negative regulator of hedgehog signaling Category: mRNA Synonyms: JBTS32|PRO1280|SUFUH|SUFUXL Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 102503987 End Site(bp): 102633535 Gene Summary: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] External Links: Ensembl ID: ENSG00000107882 HGNC ID: HGNC:16466 Entrez Gene: 51684

Expression Profile of SUFU Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-155-5p YES NO YES hsa-miR-194-5p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-371a-5p YES NO YES hsa-miR-378a-3p YES NO YES hsa-miR-383-5p YES YES NO hsa-miR-422a YES NO YES hsa-miR-873-5p YES NO YES Display: