ctcRbase

Entry Detail

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General Information

Database ID: SKCM09258 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TRIM3 Full Name: tripartite motif containing 3 Category: mRNA Synonyms: BERP|HAC1|RNF22|RNF97 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 6448613 End Site(bp): 6474459 Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000110171 HGNC ID: HGNC:10064 Entrez Gene: 10612

Expression Profile of TRIM3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-137 YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-362-5p YES NO YES hsa-miR-454-3p YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES Display: