Entry Detail



General Information

Database ID:SKCM09346
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PJA1
Full Name:praja ring finger ubiquitin ligase 1
Category:mRNA
Synonyms:PRAJA1|RNF70
Chromosome:chrX
Strand:-
Coordinate:
Start Site(bp):69160851End Site(bp):69165793
Gene Summary:This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
External Links:
Ensembl ID:ENSG00000181191
HGNC ID:HGNC:16648
Entrez Gene:64219



Expression Profile of PJA1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-155-5p
YES
YES
NO
hsa-miR-190a-5p
YES
YES
NO
hsa-miR-190b
YES
YES
NO
hsa-miR-194-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-551a
YES
YES
NO
hsa-miR-551b-3p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
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