Entry Detail



General Information

Database ID:SKCM09350
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ATG4A
Full Name:autophagy related 4A cysteine peptidase
Category:mRNA
Synonyms:APG4A|AUTL2
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):108091668End Site(bp):108154671
Gene Summary:Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016]
External Links:
Ensembl ID:ENSG00000101844
HGNC ID:HGNC:16489
Entrez Gene:115201



Expression Profile of ATG4A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-137
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-224-5p
YES
YES
NO
hsa-miR-24-3p
YES
YES
YES
hsa-miR-410-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-505-3p
YES
YES
NO
hsa-miR-542-3p
YES
YES
YES
hsa-miR-7-5p
YES
YES
YES
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