Entry Detail



General Information

Database ID:exR0076605
RNA Name:MAZ
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):29806106End Site(bp):29811164
External Links:ENSG00000103495



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC010522.1
chr19
57819719
57858941
+
AC114490.3
chr1
34974356
34985313
-
AC124312.1
chr15
24955034
25000276
+
AC131160.1
chr3
183815568
183884889
-
AC245033.1
chr15
82536788
82573194
-
ACAD9
chr3
128879596
128916067
+
ACOX1
chr17
75941507
75979177
-
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ACVR1
chr2
157736444
157876330
-
ADGRA3
chr4
22345071
22516066
-
ADIPOR1
chr1
202940826
202958572
-
AFDN
chr6
167826922
167972023
+
AGAP3
chr7
151085831
151144436
+
AGBL5
chr2
27042364
27070622
+
AGPAT3
chr21
43865223
43987592
+
AHDC1
chr1
27534035
27604431
-
AK2
chr1
33007940
33080996
-
AKAP11
chr13
42272152
42323261
+
AL121753.1
chr20
35267885
35280043
-
AL139011.2
chr1
160216800
160285130
-
AL162417.1
chr9
133098121
133163914
-
AL928654.3
chr14
105487199
105492267
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-29a-3p
chr7
130876748
130876769
-
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-1181
chr19
10403505
10403525
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC009133.1
chr16
29808636
29821252
-
AC009133.5
chr16
29808679
29812227
+
AC011445.1
chr19
39314651
39320858
-
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC026464.2
chr16
69463844
69466264
+
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA