exRNAdisease

General Information

Database ID:

exR0079628

RNA Name:

PRRC2A

RNA Type:

mRNA

Chromosome:

chr6

Starnd:

Coordinate:

Start Site(bp):

31620715

End Site(bp):

31637771

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ABCB10	chr1	229516582	229558707	-
ABHD16A	chr6	31686955	31703356	-
ABLIM1	chr10	114431113	114768061	-
AC011448.1	chr19	19516227	19536076	+
AC011462.1	chr19	41350853	41425001	+
AC022384.1	chr3	10249372	10285796	+
AC068580.4	chr11	1734821	1763954	-
AC104109.3	chr5	134167170	134226071	-
AC118549.1	chr1	77562416	77683419	-
ACADVL	chr17	7217125	7225266	+
ACAP3	chr1	1292390	1309609	-
ACTG1	chr17	81509971	81523847	-
ACTR3	chr2	113890063	113962596	+
ADIPOR1	chr1	202940826	202958572	-
ADO	chr10	62804720	62808479	+
AGPAT5	chr8	6708642	6761503	+
AHNAK	chr11	62433542	62556235	-
AIG1	chr6	143060496	143341058	+
AKT1	chr14	104769349	104795751	-
AKT2	chr19	40230317	40285536	-
AL132780.3	chr14	22946270	22982258	-
AL136295.5	chr14	24147548	24166452	+
AL136454.1	chr1	192716132	192716653	+
ALDH9A1	chr1	165662216	165698863	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004528.1	chr19	999796	1002757	-
AC007406.5	chr12	273954	277123	-
AC012236.1	chr15	31221999	31230838	-
AC069185.1	chr8	11797928	11802568	-
AC132217.1	chr11	2129121	2129964	-
AD000090.1	chr19	35557956	35581954	+
AGAP11	chr10	86970741	87010126	+
AL136982.1	chr10	86992406	87010203	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference