Entry Detail



General Information

Database ID:exR0080037
RNA Name:RAN
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):130872037End Site(bp):130877678
External Links:ENSG00000132341



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABT1
chr6
26596953
26600739
+
AC004997.1
chr22
30285238
30299482
-
AC006030.1
chr2
74211604
74363377
-
AC010132.3
chr7
42909273
42932174
-
AC092073.1
chr19
34396315
34409364
+
AC124312.1
chr15
24955034
25000276
+
AC135050.2
chr16
31083439
31094956
-
ACAA2
chr18
49782164
49813953
-
ACADVL
chr17
7217125
7225266
+
ACIN1
chr14
23058564
23095614
-
ACO1
chr9
32384603
32454769
+
ACO2
chr22
41469117
41528989
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR5
chr20
38748460
38772520
+
ADAT3
chr19
1905399
1913447
+
ADCY3
chr2
24819169
24919839
-
ADGRG1
chr16
57610652
57665580
+
ADH5
chr4
99070978
99088801
-
ADSL
chr22
40346500
40390463
+
AEN
chr15
88621337
88632281
+
AFDN
chr6
167826922
167972023
+
AGO3
chr1
35930718
36072500
+
AGPAT3
chr21
43865223
43987592
+
AIF1L
chr9
131096476
131123152
+
AKAP1
chr17
57085092
57121346
+
AKIRIN1
chr1
38991276
39006059
+
AL021546.1
chr12
120438198
120460006
+
AL022238.4
chr22
40346529
40410054
+
AL136295.4
chr14
24180395
24190416
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302a-5p
chr4
112648224
112648246
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012236.1
chr15
31221999
31230838
-
AC079781.5
chr7
97851688
97972985
-
AC106864.1
chr4
112693047
112706810
-
AC113189.4
chr17
7439506
7445966
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA