exRNAdisease

General Information

Database ID:

exR0080569

RNA Name:

RPL10

RNA Type:

mRNA

Chromosome:

chrX

Starnd:

Coordinate:

Start Site(bp):

154389955

End Site(bp):

154409168

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ABCD4	chr14	74285269	74303055	-
ABRACL	chr6	139028745	139043302	+
AC004832.3	chr22	30409255	30428990	+
AC006064.6	chr12	6556886	6607367	-
AC010132.3	chr7	42909273	42932174	-
AC010422.3	chr19	12643831	12648397	-
AC011455.2	chr19	38915404	38949855	-
AC048338.1	chr12	122207779	122266423	-
AC055811.2	chr17	17202649	17237185	-
ACO2	chr22	41469117	41528989	+
ACTB	chr7	5527148	5563784	-
ADAL	chr15	43330657	43354555	+
ADAR	chr1	154582057	154628013	-
ADD3	chr10	109996368	110135565	+
ADSL	chr22	40346500	40390463	+
AEN	chr15	88621337	88632281	+
AGBL5	chr2	27042364	27070622	+
AHCY	chr20	34280268	34311802	-
AK2	chr1	33007940	33080996	-
AKR7A2	chr1	19303965	19312146	-
AL022238.4	chr22	40346529	40410054	+
AL133352.1	chr10	100505628	100529881	-
AL136295.5	chr14	24147548	24166452	+
AL590764.2	chrX	71103987	71111575	-
ALAS1	chr3	52198086	52214327	+
ALDH16A1	chr19	49453225	49471050	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-6891-3p	chr6	31355228	31355248	-
hsa-miR-7847-3p	chr11	1880105	1880125	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC002550.2	chr16	19694035	19694428	-
AC060766.7	chr17	35406684	35409768	-
AC092490.1	chr12	8788253	8795789	+
AL035446.1	chr6	140845958	140852924	-
AL121992.1	chr1	15586136	15603626	-
AL132780.1	chr14	22929607	22956374	+
AL138828.1	chr6	135991936	136225751	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference