exRNAdisease

General Information

Database ID:

exR0080570

RNA Name:

RPL10A

RNA Type:

mRNA

Chromosome:

chr6

Starnd:

Coordinate:

Start Site(bp):

35468401

End Site(bp):

35470785

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AAAS	chr12	53307456	53324864	-
AAGAB	chr15	67200667	67255195	-
AAMP	chr2	218264123	218270257	-
ABLIM1	chr10	114431113	114768061	-
AC004922.1	chr7	99325879	99394653	+
AC007192.1	chr19	18153158	18178117	+
AC011530.1	chr19	45779437	45785973	-
AC040162.1	chr16	67929614	67936017	-
AC069368.1	chr15	64841883	64930920	+
AC087289.3	chr17	75898645	75930129	-
AC090360.1	chr18	80034346	80097088	+
AC091167.2	chr15	90249556	90272208	+
AC105052.3	chr7	102637049	102671641	-
AC119396.1	chr19	7348943	7383385	+
ACACA	chr17	37084992	37406836	-
ACBD6	chr1	180269653	180502954	-
ACTR2	chr2	65227753	65271253	+
ADD3	chr10	109996368	110135565	+
ADSL	chr22	40346500	40390463	+
AGBL5	chr2	27042364	27070622	+
AHCYL1	chr1	109984765	110023742	+
AKAP13	chr15	85380571	85749358	+
AKNA	chr9	114334156	114394405	-
AL022238.4	chr22	40346529	40410054	+
AL136454.1	chr1	192716132	192716653	+
ALDOA	chr16	30064164	30070457	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-7111-5p	chr6	35470509	35470530	+
hsa-miR-7111-3p	chr6	35470558	35470579	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC012615.1	chr19	1874871	1876169	-
AC020663.1	chr16	4730115	4752565	-
AC023509.1	chr12	53441741	53467528	+
AC063949.2	chr12	92421531	92483680	+
AC067930.3	chr8	143541973	143549729	-
AC126365.1	chr17	20788071	20789584	+
AC132217.1	chr11	2129121	2129964	-
AL022311.1	chr22	37876148	37895563	+
AL110115.2	chr20	31580890	31581214	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference