exRNAdisease

General Information

Database ID:

exR0080577

RNA Name:

RPL15

RNA Type:

mRNA

Chromosome:

chr3

Starnd:

Coordinate:

Start Site(bp):

23916545

End Site(bp):

23924374

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADPRHL2	chr1	36088892	36093932	+
AIF1L	chr9	131096476	131123152	+
AK2	chr1	33007940	33080996	-
AAGAB	chr15	67200667	67255195	-
AC026464.4	chr16	69299682	69322700	+
AL513165.2	chr9	37512547	37592469	-
ALDOA	chr16	30064164	30070457	+
AKR1A1	chr1	45550543	45570049	+
ABHD14B	chr3	51968510	51983409	-
ACO1	chr9	32384603	32454769	+
ACBD3	chr1	226144679	226186741	-
AKAP11	chr13	42272152	42323261	+
AC245033.1	chr15	82536788	82573194	-
ACTB	chr7	5527148	5563784	-
ADH5	chr4	99070978	99088801	-
ACADM	chr1	75724347	75787575	+
ACTR1B	chr2	97655939	97664044	-
AK4	chr1	65147549	65232145	+
AC010422.3	chr19	12643831	12648397	-
ADRM1	chr20	62302093	62308862	+
ALAS1	chr3	52198086	52214327	+
AL358113.1	chr9	69035747	69255187	+
AL022238.4	chr22	40346529	40410054	+
AHCY	chr20	34280268	34311802	-
AL713999.1	chr1	155169409	155187272	-
AC008982.1	chr19	38817471	38840178	-
ACTG2	chr2	73892314	73919865	+
AC005258.1	chr19	2269525	2341172	+
ADSL	chr22	40346500	40390463	+
ALDH9A1	chr1	165662216	165698863	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007952.4	chr17	19112000	19112636	-
AC010642.2	chr19	58309727	58327248	-
AC012531.1	chr12	54019910	54022589	+
AC016876.2	chr17	7581964	7584086	-
AC020978.7	chr16	68224713	68227734	+
AC023509.1	chr12	53441741	53467528	+
AC024075.2	chr19	16633797	16635269	-
AC093001.1	chr3	149284782	149333653	+
AC245014.3	chr1	145281116	145281462	+
AC246817.2	chr8	2648075	2728577	-
AD000090.1	chr19	35557956	35581954	+
AL022311.1	chr22	37876148	37895563	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference