Entry Detail



General Information

Database ID:exR0080599
RNA Name:RPL35
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):124857880End Site(bp):124861981
External Links:ENSG00000136942



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAR2
chr20
36236459
36270918
+
AC002985.1
chr19
18907013
18934397
-
AC005258.1
chr19
2269525
2341172
+
AC010323.1
chr19
8308283
8321379
-
AC010422.3
chr19
12643831
12648397
-
AC040162.1
chr16
67929614
67936017
-
AC093525.1
chr16
2513965
2527955
+
AC099811.2
chr17
42119674
42154916
-
AC105052.1
chr7
102582523
102642869
-
AC120057.2
chr17
7240427
7244635
-
ACACA
chr17
37084992
37406836
-
ACCS
chr11
44065925
44084237
+
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ACOT7
chr1
6264269
6394391
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADCK2
chr7
140672945
140696261
+
ADD1
chr4
2843857
2930076
+
ADPGK
chr15
72751369
72785846
-
ADSL
chr22
40346500
40390463
+
AFG3L2
chr18
12328944
12377227
-
AGBL5
chr2
27042364
27070622
+
AHCY
chr20
34280268
34311802
-
AL022238.4
chr22
40346529
40410054
+
AL136531.2
chr20
1317571
1393096
-
AL928654.3
chr14
105487199
105492267
+
ALDH7A1
chr5
126531200
126595362
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC026362.1
chr12
122975320
122982907
+
AC068473.5
chr18
79677287
79679358
-
AC105036.3
chr15
75527150
75601205
-
AL021707.1
chr22
38739003
38749041
+
AL022311.1
chr22
37876148
37895563
+
AL138963.1
chr13
45350323
45351350
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA