Entry Detail



General Information

Database ID:exR0080605
RNA Name:RPL37
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):40825262End Site(bp):40835222
External Links:ENSG00000145592



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005837.2
chr17
76732978
76738522
+
AC138811.2
chr16
18788063
18801519
-
AGAP4
chr10
45825594
45853875
-
AHDC1
chr1
27534035
27604431
-
AL360181.3
chr10
133380017
133420271
+
ACTR2
chr2
65227753
65271253
+
ALDOA
chr16
30064164
30070457
+
AKR1C1
chr10
4963253
4983283
+
AC073896.1
chr12
56285916
56316059
-
AC009690.1
chr15
72284727
72375981
-
AC010422.5
chr19
12664828
12669397
-
ACTG1
chr17
81509971
81523847
-
AICDA
chr12
8602170
8612867
-
ABCC5
chr3
183919934
184017939
-
AC005258.1
chr19
2269525
2341172
+
AC018523.2
chr11
14493783
14520344
-
A1BG
chr19
58345178
58353492
-
AFTPH
chr2
64524305
64593005
+
AL590132.1
chr1
210858125
211134146
-
ACTB
chr7
5527148
5563784
-
ACKR3
chr2
236567787
236582354
+
AGO4
chr1
35808016
35857890
+
AC135050.2
chr16
31083439
31094956
-
AHCYL1
chr1
109984765
110023742
+
AKT3
chr1
243488233
243851079
-
AGAP1
chr2
235494043
236131800
+
ABHD14B
chr3
51968510
51983409
-
AKIRIN1
chr1
38991276
39006059
+
AC008750.8
chr19
51350373
51368099
-
ADIPOR2
chr12
1688574
1788674
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302c-3p
chr4
112648366
112648388
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC012313.3
chr19
58346854
58362751
-
AC113414.1
chr5
162424042
163437326
-
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
AL022311.1
chr22
37876148
37895563
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA