exRNAdisease

General Information

Database ID:

exR0080639

RNA Name:

RPS11

RNA Type:

mRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

49496365

End Site(bp):

49499708

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC245033.1	chr15	82536788	82573194	-
ADCY1	chr7	45574140	45723116	+
ADAR	chr1	154582057	154628013	-
AK2	chr1	33007940	33080996	-
ADGRL1	chr19	14147743	14206187	-
ADH5	chr4	99070978	99088801	-
AC131160.1	chr3	183815568	183884889	-
AAGAB	chr15	67200667	67255195	-
ACTG1	chr17	81509971	81523847	-
AL138752.2	chr9	37588413	38068687	-
ABCE1	chr4	145098288	145129524	+
AIP	chr11	67483026	67491103	+
AC010422.3	chr19	12643831	12648397	-
AC099811.2	chr17	42119674	42154916	-
AC079594.2	chr3	160227454	160449829	-
AL603832.3	chr1	112702614	112711433	-
ABHD18	chr4	127965306	128039927	+
ADGRL2	chr1	81306160	81992436	+
AC138811.2	chr16	18788063	18801519	-
AKIRIN1	chr1	38991276	39006059	+
AL162231.3	chr9	34646645	34657113	+
ALDH18A1	chr10	95605941	95656711	-
AC004922.1	chr7	99325879	99394653	+
ACSS2	chr20	34872146	34927962	+
AC007192.1	chr19	18153158	18178117	+
AC005258.1	chr19	2269525	2341172	+
ADAM10	chr15	58588809	58749791	-
AFDN	chr6	167826922	167972023	+
AL133352.1	chr10	100505628	100529881	-
ALDOA	chr16	30064164	30070457	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-210-3p	chr11	568112	568133	-
hsa-miR-632	chr17	32350169	32350187	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004687.1	chr17	58330884	58332508	-
AC010624.2	chr19	50075123	50075902	+
AC108134.2	chr16	3156736	3157483	-
AD000090.1	chr19	35557956	35581954	+
AL117378.1	chr6	131901963	131920565	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference