Entry Detail



General Information

Database ID:exR0080641
RNA Name:RPS13
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):17074388End Site(bp):17077715
External Links:ENSG00000110700



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007192.1
chr19
18153158
18178117
+
AC008764.1
chr19
16479067
16628204
-
AC010323.1
chr19
8308283
8321379
-
AC015813.2
chr17
57989038
58007246
-
ACAD9
chr3
128879596
128916067
+
ACAT2
chr6
159762045
159779112
+
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ADD1
chr4
2843857
2930076
+
ADGRL1
chr19
14147743
14206187
-
ADK
chr10
74151202
74709963
+
ADSL
chr22
40346500
40390463
+
AGO2
chr8
140520156
140635633
-
AHCYL1
chr1
109984765
110023742
+
AHNAK
chr11
62433542
62556235
-
AHSA1
chr14
77457870
77469472
+
AKAP8
chr19
15353385
15379798
-
AKAP9
chr7
91940867
92110673
+
AKT1
chr14
104769349
104795751
-
AL022238.4
chr22
40346529
40410054
+
AL049629.2
chr11
33698261
33722467
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3651
chr9
92292461
92292484
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC073389.1
chr10
73625996
73626790
+
AC113189.4
chr17
7439506
7445966
+
AL033543.1
chr22
44102779
44116232
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA