exRNAdisease

General Information

Database ID:

exR0080645

RNA Name:

RPS16

RNA Type:

mRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

39433137

End Site(bp):

39435949

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AL928654.3	chr14	105487199	105492267	+
ACTA2	chr10	88935074	88991339	-
ACOT9	chrX	23701055	23766475	-
AC009690.1	chr15	72284727	72375981	-
ACTN4	chr19	38647649	38731589	+
ALDOA	chr16	30064164	30070457	+
ADORA2A	chr22	24417879	24442357	+
ACTL6A	chr3	179562886	179588407	+
AKAP5	chr14	64465499	64474503	+
ADGRG6	chr6	142301854	142446266	+
AC010422.3	chr19	12643831	12648397	-
AICDA	chr12	8602170	8612867	-
AHSA1	chr14	77457870	77469472	+
AL121845.2	chr20	63738270	63740398	+
ACIN1	chr14	23058564	23095614	-
AL121845.3	chr20	63708864	63739103	+
ABCB8	chr7	151028422	151047782	+
ADM	chr11	10305073	10307397	+
ADIPOR2	chr12	1688574	1788674	+
ACO2	chr22	41469117	41528989	+
AEN	chr15	88621337	88632281	+
ACAA2	chr18	49782164	49813953	-
AC010323.1	chr19	8308283	8321379	-
AHCY	chr20	34280268	34311802	-
ADI1	chr2	3497366	3519531	-
AC004922.1	chr7	99325879	99394653	+
ADD1	chr4	2843857	2930076	+
ABCF1	chr6	30571393	30597179	+
AC124312.1	chr15	24955034	25000276	+
AK2	chr1	33007940	33080996	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-492	chr12	94834427	94834449	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC023509.1	chr12	53441741	53467528	+
AC027020.2	chr15	100547765	100550153	-
AC067852.1	chr17	42536510	42562062	+
AC096536.3	chr1	54874672	54883664	+
AC104596.1	chr4	142933195	143184861	-
AC245014.3	chr1	145281116	145281462	+
AD000090.1	chr19	35557956	35581954	+
AL132780.1	chr14	22929607	22956374	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference