exRNAdisease

General Information

Database ID:

exR0080647

RNA Name:

RPS18

RNA Type:

mRNA

Chromosome:

chr6

Starnd:

Coordinate:

Start Site(bp):

33272075

End Site(bp):

33276511

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AHCY	chr20	34280268	34311802	-
AKIRIN1	chr1	38991276	39006059	+
AC015802.6	chr17	76563710	76570544	-
AC024592.3	chr19	5866171	5903787	-
ABRACL	chr6	139028745	139043302	+
ABTB2	chr11	34150987	34358010	-
ADGRL2	chr1	81306160	81992436	+
AIFM1	chrX	130129362	130165887	-
ALDOA	chr16	30064164	30070457	+
AKR1A1	chr1	45550543	45570049	+
AC005258.1	chr19	2269525	2341172	+
AFG3L2	chr18	12328944	12377227	-
ABCB7	chrX	75051048	75156732	-
AGO2	chr8	140520156	140635633	-
AASDH	chr4	56338287	56387508	-
AKT1S1	chr19	49869033	49878459	-
AC011462.1	chr19	41350853	41425001	+
ACTB	chr7	5527148	5563784	-
AEBP2	chr12	19404045	19720801	+
ACTR3	chr2	113890063	113962596	+
AAR2	chr20	36236459	36270918	+
AC008982.1	chr19	38817471	38840178	-
ACAA2	chr18	49782164	49813953	-
AC007040.2	chr2	70939318	70995336	-
ADRA2A	chr10	111077029	111080907	+
AC011005.1	chr7	129126518	129130793	+
AC023055.1	chr12	55757275	55827546	-
ACTR2	chr2	65227753	65271253	+
AC010422.3	chr19	12643831	12648397	-
AC073508.2	chr17	40627356	40665141	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004080.6	chr7	27128969	27152561	-
AC004687.1	chr17	58330884	58332508	-
AC021078.1	chr5	149494314	149504670	-
AC040162.3	chr16	67882461	67886367	+
AC091564.7	chr11	6610883	6616594	-
AC105339.2	chr15	82752884	82757208	+
AC138089.1	chr1	248484245	248485484	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference