Entry Detail



General Information

Database ID:exR0080650
RNA Name:RPS2
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):1962058End Site(bp):1964841
External Links:ENSG00000140988



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC087289.3
chr17
75898645
75930129
-
ADSL
chr22
40346500
40390463
+
ACTR3
chr2
113890063
113962596
+
ADPRH
chr3
119579268
119589945
+
ADAR
chr1
154582057
154628013
-
AC138811.2
chr16
18788063
18801519
-
ALDOA
chr16
30064164
30070457
+
AHCY
chr20
34280268
34311802
-
AL133352.1
chr10
100505628
100529881
-
AC093525.2
chr16
2496032
2520218
+
AC007192.1
chr19
18153158
18178117
+
AL590764.2
chrX
71103987
71111575
-
AC004832.3
chr22
30409255
30428990
+
AL669918.1
chr6
32813767
32838822
-
AC024592.3
chr19
5866171
5903787
-
AC010422.3
chr19
12643831
12648397
-
AL136295.1
chr14
24189157
24213473
-
ADGRG5
chr16
57542643
57591681
+
ADGRB1
chr8
142449430
142545009
+
AL021546.1
chr12
120438198
120460006
+
AC093525.1
chr16
2513965
2527955
+
AL022238.4
chr22
40346529
40410054
+
AGAP4
chr10
45825594
45853875
-
AC092143.1
chr16
89919165
89936092
+
AC015813.2
chr17
57989038
58007246
-
AC107871.1
chr15
68184032
68229718
-
AGAP3
chr7
151085831
151144436
+
AL603832.3
chr1
112702614
112711433
-
ACTG1
chr17
81509971
81523847
-
AC069503.2
chr12
121888809
121921470
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1244
chr2
231713368
231713393
+
hsa-miR-7111-3p
chr6
35470558
35470579
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010542.4
chr16
66549280
66551189
+
AC087190.3
chr16
9104848
9113181
+
AC087521.3
chr11
43921059
44001157
+
AC108134.2
chr16
3156736
3157483
-
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA