exRNAdisease

General Information

Database ID:

exR0080666

RNA Name:

RPS5

RNA Type:

mRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

58386400

End Site(bp):

58394806

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AGFG2	chr7	100539203	100568220	+
AL358113.1	chr9	69035747	69255187	+
AKAP1	chr17	57085092	57121346	+
ACO2	chr22	41469117	41528989	+
AL022238.4	chr22	40346529	40410054	+
AC004832.3	chr22	30409255	30428990	+
AC007192.1	chr19	18153158	18178117	+
AC139530.2	chr17	81703371	81720539	+
AC010422.3	chr19	12643831	12648397	-
AC092073.1	chr19	34396315	34409364	+
AC040162.1	chr16	67929614	67936017	-
ABRACL	chr6	139028745	139043302	+
ACTN4	chr19	38647649	38731589	+
AHDC1	chr1	27534035	27604431	-
AHCYL1	chr1	109984765	110023742	+
AHCY	chr20	34280268	34311802	-
ACTR1B	chr2	97655939	97664044	-
ACTB	chr7	5527148	5563784	-
ALDOA	chr16	30064164	30070457	+
AK2	chr1	33007940	33080996	-
AC008763.3	chr19	7678501	7682854	+
AC002985.1	chr19	18907013	18934397	-
AC011462.1	chr19	41350853	41425001	+
ABHD10	chr3	111979010	111993368	+
AC018523.2	chr11	14493783	14520344	-
AC104452.1	chr3	49416777	49429314	-
AHSA1	chr14	77457870	77469472	+
ABCC1	chr16	15949577	16143074	+
ADSL	chr22	40346500	40390463	+
AACS	chr12	125065434	125143333	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-1244	chr2	231713368	231713393	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC026362.1	chr12	122975320	122982907	+
AC091564.7	chr11	6610883	6616594	-
AC121761.1	chr12	75483454	75489820	-
AD000090.1	chr19	35557956	35581954	+
AL121832.3	chr20	62402236	62405935	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference