exRNAdisease

General Information

Database ID:

exR0080679

RNA Name:

RPS8

RNA Type:

mRNA

Chromosome:

chr1

Starnd:

Coordinate:

Start Site(bp):

44775251

End Site(bp):

44778779

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACVR1B	chr12	51951699	51997078	+
AL021546.1	chr12	120438198	120460006	+
AC073508.2	chr17	40627356	40665141	-
AC008758.1	chr19	12461559	12551474	-
ACAT1	chr11	108116695	108147603	+
AC120057.2	chr17	7240427	7244635	-
AC138811.2	chr16	18788063	18801519	-
ADNP	chr20	50888916	50931437	-
AHCYL1	chr1	109984765	110023742	+
AGL	chr1	99850361	99924023	+
ABI3	chr17	49210411	49223225	+
ACTG1	chr17	81509971	81523847	-
ACTR1B	chr2	97655939	97664044	-
ACTA2	chr10	88935074	88991339	-
AL136295.5	chr14	24147548	24166452	+
ABRACL	chr6	139028745	139043302	+
AKIRIN1	chr1	38991276	39006059	+
AKT1	chr14	104769349	104795751	-
ACTA1	chr1	229431245	229434098	-
AL669918.1	chr6	32813767	32838822	-
AHRR	chr5	271670	438291	+
ABCD4	chr14	74285269	74303055	-
AGPAT3	chr21	43865223	43987592	+
AEN	chr15	88621337	88632281	+
AC002985.1	chr19	18907013	18934397	-
AKR7A2	chr1	19303965	19312146	-
ADRM1	chr20	62302093	62308862	+
AC022384.1	chr3	10249372	10285796	+
ADAR	chr1	154582057	154628013	-
ADD1	chr4	2843857	2930076	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-92a-3p	chrX	134169544	134169565	-
hsa-miR-367-3p	chr4	112647877	112647898	-

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC063949.2	chr12	92421531	92483680	+
AC090772.3	chr18	24159509	24162211	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference