exRNAdisease

General Information

Database ID:

exR0080680

RNA Name:

RPS9

RNA Type:

mRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

54200809

End Site(bp):

54249003

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADRM1	chr20	62302093	62308862	+
AL021546.1	chr12	120438198	120460006	+
ALDH16A1	chr19	49453225	49471050	+
AC007192.1	chr19	18153158	18178117	+
AHSA1	chr14	77457870	77469472	+
ADGRG5	chr16	57542643	57591681	+
AGAP4	chr10	45825594	45853875	-
AC105052.3	chr7	102637049	102671641	-
ABRACL	chr6	139028745	139043302	+
ADAM8	chr10	133262420	133276868	-
AGGF1	chr5	77029251	77065234	+
ADAM10	chr15	58588809	58749791	-
ACTB	chr7	5527148	5563784	-
AKT1S1	chr19	49869033	49878459	-
AC004922.1	chr7	99325879	99394653	+
ACAA2	chr18	49782164	49813953	-
AC120057.2	chr17	7240427	7244635	-
AHCY	chr20	34280268	34311802	-
ACVR2B	chr3	38453890	38493142	+
AASDHPPT	chr11	106075501	106098699	+
ACER3	chr11	76860867	77026797	+
ACOT2	chr14	73567620	73575658	+
AC245033.1	chr15	82536788	82573194	-
ABLIM1	chr10	114431113	114768061	-
AC138811.2	chr16	18788063	18801519	-
ADNP	chr20	50888916	50931437	-
AFDN	chr6	167826922	167972023	+
ABHD17B	chr9	71862452	71910931	-
AKNA	chr9	114334156	114394405	-
ACTG1	chr17	81509971	81523847	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-3615	chr17	74748663	74748683	+
hsa-miR-4707-5p	chr14	22956998	22957020	-

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004069.1	chr4	105137280	105140619	-
AC022400.3	chr10	73674295	73730466	-
AC073508.3	chr17	40648300	40649718	+
AC132217.1	chr11	2129121	2129964	-
AC245014.3	chr1	145281116	145281462	+
AD000090.1	chr19	35557956	35581954	+
AL139089.1	chr13	52651305	52652279	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference