exRNAdisease

General Information

Database ID:

exR0080903

RNA Name:

SCD

RNA Type:

mRNA

Chromosome:

chr10

Starnd:

Coordinate:

Start Site(bp):

100347233

End Site(bp):

100364826

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC010132.3	chr7	42909273	42932174	-
AC018523.2	chr11	14493783	14520344	-
AC048338.1	chr12	122207779	122266423	-
AC092143.1	chr16	89919165	89936092	+
AC120057.2	chr17	7240427	7244635	-
AC138811.2	chr16	18788063	18801519	-
ACP1	chr2	264140	278283	+
ACP6	chr1	147629652	147670524	-
ACTB	chr7	5527148	5563784	-
ACTG1	chr17	81509971	81523847	-
ACTR2	chr2	65227753	65271253	+
ADAR	chr1	154582057	154628013	-
ADSL	chr22	40346500	40390463	+
AEBP2	chr12	19404045	19720801	+
AGBL5	chr2	27042364	27070622	+
AGPS	chr2	177392757	177559299	+
AIG1	chr6	143060496	143341058	+
AKIRIN2	chr6	87674860	87702233	-
AL022238.4	chr22	40346529	40410054	+
ALDH7A1	chr5	126531200	126595362	-
ALDH9A1	chr1	165662216	165698863	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-7-5p	chr19	4770700	4770723	+
hsa-miR-185-5p	chr22	20033153	20033174	+
hsa-miR-1321	chrX	85835832	85835849	+
hsa-miR-1197	chr14	101025620	101025640	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC004816.1	chr14	70809841	70815994	+
AC005618.1	chr5	141326210	141329357	+
AC009446.1	chr8	71675300	71702786	+
AC010719.1	chr7	25948657	25949403	-
AC106795.2	chr5	177950335	177963960	+
AC106864.1	chr4	112693047	112706810	-
AC124068.2	chr15	89335053	89336161	+
AC124283.3	chr17	82578023	82578616	+
AC126365.1	chr17	20788071	20789584	+
AL132780.1	chr14	22929607	22956374	+

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference