Entry Detail



General Information

Database ID:exR0084517
RNA Name:XRCC5
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):216107464End Site(bp):216206303
External Links:ENSG00000079246



Disease Information

Disease Name:Fragile X Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D005600
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA



Expression Detail

GEO ID:GSE83556
Description:Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:Disease vs Control
Case Disease Type:Fragile X Syndrome
Case Disease SubType:NA
Case Sample:Fragile X Syndrome
Control Sample:Normal
Number of Case:22
Number of Control:18
Number of Samples:40





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC002985.1
chr19
18907013
18934397
-
AC023055.1
chr12
55757275
55827546
-
AC097637.1
chr3
52221081
52231190
-
AC107871.1
chr15
68184032
68229718
-
AC120057.2
chr17
7240427
7244635
-
AC124312.1
chr15
24955034
25000276
+
AC244197.3
chrX
149477104
149540926
-
AC245033.1
chr15
82536788
82573194
-
ACO1
chr9
32384603
32454769
+
ACSS2
chr20
34872146
34927962
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ADA
chr20
44619522
44652233
-
ADGRA3
chr4
22345071
22516066
-
ADIPOR2
chr12
1688574
1788674
+
AFF1
chr4
86935002
87141054
+
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AIMP1
chr4
106315544
106349456
+
AKIRIN1
chr1
38991276
39006059
+
AKR1A1
chr1
45550543
45570049
+
AL136295.4
chr14
24180395
24190416
-
AL162417.1
chr9
133098121
133163914
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC040162.3
chr16
67882461
67886367
+
AC136475.2
chr11
310139
311141
-
AC245033.4
chr15
82533175
82540008
-
AFDN-DT
chr6
167822103
167826812
-
Display:



Experiment Detail

GEO ID:GSE83556
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA