exRNAdisease

General Information

Database ID:

exR0084530

RNA Name:

YBX1

RNA Type:

mRNA

Chromosome:

chr1

Starnd:

Coordinate:

Start Site(bp):

42682418

End Site(bp):

42703805

External Links:

Disease Information

Disease Name:	Fragile X Syndrome
Disease Category:	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:	D005600
Type:	Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:	Fragile X Syndromes//Syndrome, Fragile X//Syndromes, Fragile X//Marker X Syndrome//Marker X Syndromes//Syndrome, Marker X//Syndromes, Marker X//Mental Retardation, X-Linked, Associated With Marxq28//X-Linked Mental Retardation and Macroorchidism//X Linked Mental Retardation and Macroorchidism//Fragile X Mental Retardation Syndrome//Martin-Bell Syndrome//Martin Bell Syndrome//Syndrome, Martin-Bell//Fra(X) Syndrome//FRAXE Syndrome//FRAXE Syndromes//Syndrome, FRAXE//Syndromes, FRAXE//Mental Retardation, X-Linked, Associated With Fragile Site Fraxe//Fragile X-F Mental Retardation Syndrome//Mar (X) Syndrome//FRAXA Syndrome//FRAXA Syndromes//Syndrome, FRAXA//Syndromes, FRAXA

Expression Detail

GEO ID:	GSE83556
Description:	Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions
Experimental Design:	Disease vs Control
Case Disease Type:	Fragile X Syndrome
Case Disease SubType:	NA
Case Sample:	Fragile X Syndrome
Control Sample:	Normal
Number of Case:	22
Number of Control:	18
Number of Samples:	40

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ABL1	chr9	130713016	130887675	+
ABR	chr17	1003518	1229738	-
AC008764.4	chr19	16577642	16660115	-
AC010422.3	chr19	12643831	12648397	-
AC092143.1	chr16	89919165	89936092	+
AC118553.2	chr1	99970011	100083321	+
AC120057.2	chr17	7240427	7244635	-
AC138811.2	chr16	18788063	18801519	-
ACAD8	chr11	134253495	134265855	+
ACKR3	chr2	236567787	236582354	+
ACTB	chr7	5527148	5563784	-
ACTG1	chr17	81509971	81523847	-
ADAM11	chr17	44758988	44781846	+
ADD2	chr2	70607618	70768225	-
ADGRL2	chr1	81306160	81992436	+
AEBP2	chr12	19404045	19720801	+
AEN	chr15	88621337	88632281	+
AFG3L2	chr18	12328944	12377227	-
AGL	chr1	99850361	99924023	+
AGO3	chr1	35930718	36072500	+
AGO4	chr1	35808016	35857890	+
AKR1E2	chr10	4786629	4848062	+
AKT1	chr14	104769349	104795751	-
AL136454.1	chr1	192716132	192716653	+
AL928654.3	chr14	105487199	105492267	+
ALDH9A1	chr1	165662216	165698863	-
ALDOA	chr16	30064164	30070457	+

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC016876.2	chr17	7581964	7584086	-
AC018521.1	chr17	47945424	47981736	+
AC245014.3	chr1	145281116	145281462	+
AL031320.2	chr6	143484979	143507327	+
AL121992.1	chr1	15586136	15603626	-

Display:

Experiment Detail

GEO ID:	GSE83556
Sample Source:	Amniotic Fluid
Source Fraction:	Supernatant
Platform:	GPL570
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	17063
Sample treatment protocol:	RNA was extracted from 5-15 mL amniotic fluid supernatant (centrifugation at 350g, 4C, 10, min).
RNA Extract protocol:	All samples were processed using the Qiagen Circulating Nucleic Acid kit with an on-column DNase digestion step to remove genomic DNA. The RNA was then purified and concentrated with the RNeasy MinElute Clean up kit and eluted in RNasefree water.
RNA library preparation protocol:	RNA was converted to cDNA and amplified using the Ovation Pico WTA kit V2 and then purified with the QIAquick PCR Purification kit. Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA)Samples were labeled using the Encore Biotin Module (NuGEN, San Carlos, CA).

Reference