Entry Detail



General Information

Database ID:exR0087373
RNA Name:hsa-miR-320d
RNA Type:miRNA
Chromosome:chr13
Starnd:-
Coordinate:
Start Site(bp):40727828End Site(bp):40727846
External Links:hsa-miR-320d



Disease Information

Disease Name:Moyamoya Disease
Disease Category:Nervous System Diseases
MeSH ID:D009072
Type:Diseases Category/Nervous System Diseases
Alias:Progressive Intracranial Occlusive Arteropathy (Moyamoya)//Moyamoya Syndrome//Moya-Moya Disease//Disease, Moya-Moya//Moya Moya Disease//Cerebrovascular Moyamoya Disease//Moyamoya Disease, Primary//Disease, Primary Moyamoya//Moyamoya Diseases, Primary//Primary Moyamoya Disease//Primary Moyamoya Diseases//Moyamoya Disease, Classic//Classic Moyamoya Disease//Disease, Classic Moyamoya//Moyamoya Disease, Secondary//Secondary Moyamoya Disease



Expression Detail

GEO ID:GSE100488
Description:Circulating miRNome profiling in Moyamoya disease-discordant monozygotic twins
Experimental Design:Disease vs Control
Case Disease Type:Moyamoya Disease
Case Disease SubType:NA
Case Sample:Moyamoya Disease
Control Sample:Normal
Number of Case:11
Number of Control:10
Number of Samples:21





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACAP2
chr3
195274745
195443044
-
ASB1
chr2
238426742
238452250
+
BLCAP
chr20
37492472
37527931
-
CGN
chr1
151510510
151538692
+
FJX1
chr11
35618460
35620865
+
GMCL1
chr2
69829660
69881384
+
MIER3
chr5
56919602
56971675
-
PFN1
chr17
4945652
4949061
-
SIN3A
chr15
75369379
75455842
-
TRIM14
chr9
98069275
98119222
-
ZCCHC2
chr18
62523025
62587709
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000417
chr12
69644908
69656342
+
hsa_circ_0000540
chr14
55799534
55821940
+
hsa_circ_0000095
chr1
95609446
95616975
+
hsa_circ_0000744
chr17
15968183
15971435
-
hsa_circ_0000652
chr15
90984737
90986710
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002044.1
chr16
73014319
73014476
-
AC016876.2
chr17
7581964
7584086
-
AC092718.4
chr16
81030770
81031485
+
AL022311.1
chr22
37876148
37895563
+
AL162258.1
chr1
153626332
153634340
-
DLEU1
chr13
50082169
50906856
+
GAS5
chr1
173858559
173868882
-
LINC00641
chr14
21200079
21206900
-
MALAT1
chr11
65497688
65506516
+
MIR3142HG
chr5
160438594
160487426
+
NEAT1
chr11
65422774
65445540
+
NR2F2-AS1
chr15
96110040
96327361
-
OIP5-AS1
chr15
41283990
41309737
+
SNHG1
chr11
62851984
62855953
-
SNHG12
chr1
28578538
28583132
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE100488
Sample Source:Blood
Source Fraction:Plasma
Platform:GPL20712
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:291
Sample treatment protocol:Whole blood samples were collected into disodium ethylenediaminotetraacetate tubes, centrifuged (4 °C, 3000 rpm, 30 minutes) immediately for plasma.
RNA Extract protocol:Total RNA was isolated from 200 uL of the pooled plasma using miRNeasy Serum/Plasma Kit (QIAGEN, Hilden, Germany).
RNA library preparation protocol:Cyanine 3-pCp-labeled microRNA was prepared from 2-uL of total RNA isolated from 200-uL of plasma, using Agilent's miRNA Complete Labeling and Hyb Kit (part number 5190-0456).



Reference

PMID:30157848
Title:Circulating miRNome profiling in Moyamoya disease-discordant monozygotic twins and endothelial microRNA expression analysis using iPS cell line
Author:Uchino H, Ito M, Kazumata K, Hama Y, Hamauchi S, Terasaka S, Sasaki H, Houkin K
Journal:BMC Med Genomics. 2018 Aug 29;11(1):72.
Description:we employed a disease discordant monozygotic twin-based study design to unmask potential confounders.