Entry Detail


General Information

Database ID:exR0093609
RNA Name:hsa-miR-3648
RNA Type:miRNA
Chromosome:chr21
Starnd:+
Coordinate:
Start Site(bp):8987026End Site(bp):8987046
External Links:hsa-miR-3648



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MT-CO2
chrMT
7586
8269
+
THAP7
chr22
20999104
21002196
-
CERS4
chr19
8206736
8262421
+
ARL8B
chr3
5122245
5180912
+
EEF1G
chr11
62559596
62574086
-
FNBP4
chr11
47716494
47767443
-
PTGES3
chr12
56663341
56688408
-
AP002990.1
chr11
62559603
62591531
-
PTCH2
chr1
44819844
44843253
-
MAPK9
chr5
180233143
180292099
-
ACTG1
chr17
81509971
81523847
-
ECPAS
chr9
111360692
111484745
-
RNF126
chr19
647526
663233
-
SF3A2
chr19
2236824
2248655
+
TPT1
chr13
45333471
45341370
-
AKIRIN2
chr6
87674860
87702233
-
LZTS3
chr20
3162617
3173592
-
AL133352.1
chr10
100505628
100529881
-
ATP6V0A2
chr12
123712353
123761755
+
SET
chr9
128683424
128696400
+
SH3GLB2
chr9
129007036
129028303
-
PAM16
chr16
4331549
4355607
-
LRRC45
chr17
82023305
82031151
+
SRRM2
chr16
2752626
2772538
+
NDUFB8
chr10
100523740
100530000
-
GAPDH
chr12
6534512
6538374
+
CORO7-PAM16
chr16
4340251
4420494
-
SKI
chr1
2228319
2310213
+
SSR2
chr1
156009048
156020951
-
ARRDC4
chr15
97960703
97973833
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.