Entry Detail


General Information

Database ID:exR0094155
RNA Name:hsa-miR-4709-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):74480175End Site(bp):74480196
External Links:hsa-miR-4709-5p



Disease Information

Disease Name:Benign Ovarian Disease
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D010049
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovarian Diseases//Disease, Ovarian//Diseases, Ovarian//Ovarian Disease



Expression Detail

GEO ID:GSE106817
Description:Integrated extracellular microRNA profiling for ovarian cancer screening
Experimental Design:Cancer vs Control
Case Disease Type:Benign Ovarian Disease
Case Disease SubType:NA
Case Sample:Benign Ovarian Disease
Control Sample:Non-Cancer
Number of Case:29
Number of Control:2759
Number of Samples:2788





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BCORL1
chrX
129981107
130058083
+
CBX2
chr17
79778148
79787983
+
CTNND1
chr11
57753243
57819546
+
DNAJB6
chr7
157335381
157417439
+
ERP29
chr12
112013348
112023449
+
LAMC1
chr1
183023420
183145592
+
ARID4B
chr1
235131634
235328219
-
CLSTN3
chr12
7129698
7158945
+
DHX16
chr6
30653119
30673006
-
GFM2
chr5
74721206
74767147
-
HNRNPL
chr19
38836388
38852347
-
HOXB13
chr17
48724763
48729178
-
HSP90AA1
chr14
102080738
102139699
-
IDH1
chr2
208236227
208266074
-
IREB2
chr15
78437431
78501453
+
MKKS
chr20
10401009
10434222
-
MSH3
chr5
80654652
80876815
+
NPC2
chr14
74476192
74494177
-
PABPC1
chr8
100685816
100722809
-
PODXL
chr7
131500262
131558217
-
PRDX5
chr11
64318121
64321811
+
SCAF8
chr6
154733325
154834244
+
TIAM2
chr6
154832697
155257723
+
UGP2
chr2
63840940
63891562
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005479.1
chr14
74474007
74474864
-
Display:



Experiment Detail

GEO ID:GSE106817
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2535
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30333487
Title:Integrated extracellular microRNA profiling for ovarian cancer screening
Author:Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda SI, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T
Journal:Nat Commun. 2018 Oct 17;9(1):4319.
Description:to develop an optimal detection method, we use microarrays to obtain comprehensive miRNA profiles from 4046 serum samples, including 428 patients with ovarian tumors.