Entry Detail


General Information

Database ID:exR0154580
RNA Name:hsa-miR-532-3p
RNA Type:miRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):50003204End Site(bp):50003225
External Links:hsa-miR-532-3p



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE113234
Description:Circulating microRNAs combined with PSA for an accurate and non-invasive prostate cancer detection
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:NA
Case Sample:Prostate Cancer
Control Sample:Healthy
Number of Case:60
Number of Control:27
Number of Samples:87





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD2
chr15
89087459
89202355
+
ABL2
chr1
179099330
179229684
-
CHD2
chr15
92900189
93027996
+
FOSL2
chr2
28392448
28417317
+
HNRNPH1
chr5
179614178
179634784
-
KIAA1522
chr1
32741830
32774970
+
NPTN
chr15
73560014
73634134
-
PACS1
chr11
66070272
66244744
+
PHC3
chr3
170086732
170181749
-
SIAH2
chr3
150741125
150763477
-
SLC7A6
chr16
68264516
68301823
+
SMG5
chr1
156249224
156282825
-
ZHX3
chr20
41178448
41317672
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL132655.2
chr20
58817132
58817725
-
KCNQ1OT1
chr11
2608328
2699994
-
LZTS1-AS1
chr8
20275773
20290458
+
MALAT1
chr11
65497688
65506516
+
MIR34AHG
chr1
9148011
9198906
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG10
chr14
95521943
95534889
-
VPS9D1-AS1
chr16
89711856
89718165
+
Display:



Experiment Detail

GEO ID:GSE113234
Sample Source:Blood
Source Fraction:Plasma
Platform:GPL19730
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1972
Sample treatment protocol:NA
RNA Extract protocol:Extraction was performed using miRNEasy serum/plasma kit from Qiagen.
RNA library preparation protocol:Briefly, 4 ul of totRNA were dephosphorylated and denaturated; then a ligation and labeling step with Cy3 was performed



Reference

PMID:30452625
Title:Circulating microRNAs combined with PSA for accurate and non-invasive prostate cancer detection
Author:Mello-Grand M, Gregnanin I, Sacchetto L, Ostano P, Zitella A, Bottoni G, Oderda M, Marra G, Munegato S, Pardini B, Naccarati A, Gasparini M, Gontero P, Chiorino G
Journal:Carcinogenesis. 2019 Apr 29;40(2):246-253.
Description:we propose to combine circulating microRNAs (miRs) with PSA, to improve the diagnostic route for PCa