exRNAdisease

Entry Detail

General Information

Database ID:

exR0197751

RNA Name:

hsa-miR-532-5p

RNA Type:

miRNA

Chromosome:

chrX

Starnd:

+

Coordinate:

Start Site(bp):

50003167

End Site(bp):

50003188

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AXL	chr19	41219223	41261766	+
CRIM1	chr2	36355778	36551135	+
DCTN4	chr5	150708440	150759109	-
LEPROTL1	chr8	30095408	30177208	+
LUZP1	chr1	23084023	23177808	-
MEX3A	chr1	156072013	156082465	-
PRRC1	chr5	127517609	127555089	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000787	chr17	54978779	54981849	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC079781.5	chr7	97851688	97972985	-
AL049796.1	chr1	93847174	93848939	+
AP000553.1	chr22	21652270	21670237	+
GAS5	chr1	173858559	173868882	-
KCNQ1OT1	chr11	2608328	2699994	-
RRN3P2	chr16	29074976	29116718	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia