exRNAdisease

Entry Detail

General Information

Database ID:

exR0198122

RNA Name:

hsa-miR-663a

RNA Type:

miRNA

Chromosome:

chr20

Starnd:

-

Coordinate:

Start Site(bp):

26208243

End Site(bp):

26208264

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
COL6A2	chr21	46098112	46132848	+
KLC2	chr11	66257294	66267860	+
REXO1	chr19	1815248	1848483	-
MIDN	chr19	1248553	1259140	+
STK35	chr20	2101827	2177038	+
MIGA2	chr9	129036621	129072082	+
SRPRA	chr11	126262938	126269144	-
KDM2A	chr11	67119263	67258082	+
JUNB	chr19	12791486	12793315	+
GNB1	chr1	1785285	1891117	-
SYVN1	chr11	65121780	65134533	-
SCN1B	chr19	35030470	35040449	+
SMAD3	chr15	67063763	67195169	+
HIF1AN	chr10	100529072	100559998	+
TNRC6A	chr16	24610209	24827632	+
ARHGAP1	chr11	46677080	46700619	-
ARL8A	chr1	202133404	202144743	-
PPDPF	chr20	63520765	63522206	+
KMT5A	chr12	123383773	123409353	+
RTL8A	chrX	135050932	135052196	-
SOX12	chr20	325595	330224	+
CYB5R3	chr22	42617840	42649392	-
PRR12	chr19	49591182	49626439	+
CAPN15	chr16	527712	554636	+
DMWD	chr19	45782947	45792845	-
BOC	chr3	113211003	113287459	+
FAM83H	chr8	143723933	143738234	-
CLSTN1	chr1	9728926	9823984	-
CALR	chr19	12938578	12944489	+
CMIP	chr16	81445170	81711762	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC008738.7	chr19	33207129	33207639	+
AC020928.2	chr19	36773712	36775908	-
AC069281.2	chr7	100572232	100578700	-
AC234582.1	chr1	155195004	155205495	+
AL137127.1	chr1	19072110	19075511	-
AL355075.4	chr14	20343048	20343685	-
AL356488.2	chr1	109100193	109100619	+
GAS5	chr1	173858559	173868882	-
MIR663AHG	chr20	26167817	26251546	-
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
SNHG25	chr17	64145970	64146476	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia