exRNAdisease

Entry Detail

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General Information

Database ID: exR0261587 RNA Name: hsa-miR-125a-5p RNA Type: miRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 51693268 End Site(bp): 51693291 External Links: hsa-miR-125a-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DDX54 chr12 113157174 113185479 - RAB3D chr19 11322068 11346270 - RYBP chr3 72371825 72446621 - TRIM65 chr17 75880335 75896951 - UGGT1 chr2 128091200 128195677 + ZBTB39 chr12 56998836 57006546 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000370 chr11 128628009 128651918 + hsa_circ_0001723 chr7 91924202 91948826 + hsa_circ_0001492 chr5 65284462 65290692 + hsa_circ_0000494 chr13 76134888 76143643 + hsa_circ_0001307 chr3 51575513 51624575 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007780.1 chr17 68413623 68524949 + AC022167.2 chr16 8848105 8860456 + AC084082.1 chr8 66112667 66126632 + AC108134.2 chr16 3156736 3157483 - AC245014.3 chr1 145281116 145281462 + AL049840.4 chr14 103694516 103695050 - AL132780.1 chr14 22929607 22956374 + AL137782.1 chr13 75549773 75807120 + AL162258.1 chr1 153626332 153634340 - DANCR chr4 52712404 52720351 + KCNQ1OT1 chr11 2608328 2699994 - NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA