exRNAdisease

Entry Detail

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General Information

Database ID: exR0261609 RNA Name: hsa-miR-1270 RNA Type: miRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 20399320 End Site(bp): 20399342 External Links: hsa-miR-1270

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MIEF1 chr22 39499432 39518132 + WIPF2 chr17 40219304 40284136 + GBA2 chr9 35736866 35749228 - HIF1AN chr10 100529072 100559998 + TCF12 chr15 56918623 57299281 + CDC42EP2 chr11 65314866 65322417 + LITAF chr16 11547722 11636381 - GRHL2 chr8 101492439 101669726 + PRLR chr5 35048756 35230487 - PATL1 chr11 59636716 59669037 - CACNG4 chr17 66964707 67033398 + ZNF652 chr17 49289206 49362473 - CDC37 chr19 10391133 10420121 - AGFG1 chr2 227472152 227561214 + SMG7 chr1 183472216 183598246 + TRIP6 chr7 100867387 100873454 + FN1 chr2 215360440 215436073 - DCBLD2 chr3 98795941 98901695 - BEND3 chr6 107065182 107115269 - NACC1 chr19 13116862 13141147 + TPM4 chr19 16067021 16103002 + TLNRD1 chr15 81000923 81005788 + SRGAP2 chr1 206203345 206464443 + PITPNA chr17 1517718 1562792 - FAM78A chr9 131258076 131276510 - ATP6V1B2 chr8 20197381 20226819 + VGF chr7 101162509 101165569 - PLAGL2 chr20 32192504 32207743 - PCDH10 chr4 133149294 133208606 + B4GALT5 chr20 49632945 49713878 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001247 chr22 46125304 46136418 + hsa_circ_0001159 chr20 40161688 40179999 - hsa_circ_0000471 chr13 33091993 33101669 - hsa_circ_0001666 chr6 170626457 170639638 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC239868.1 chr1 149861271 149862504 + AC245033.4 chr15 82533175 82540008 - AP000233.2 chr21 25095022 25103670 + MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - NR2F2-AS1 chr15 96110040 96327361 - OIP5-AS1 chr15 41283990 41309737 + SNHG12 chr1 28578538 28583132 - SNHG8 chr4 118278709 118285316 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA