exRNAdisease

Entry Detail

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General Information

Database ID: exR0262463 RNA Name: hsa-miR-4426 RNA Type: miRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 192716333 End Site(bp): 192716349 External Links: hsa-miR-4426

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand UFC1 chr1 161152776 161158856 + NDUFA4 chr7 10931943 10940153 - N4BP3 chr5 178113532 178126081 + MTRNR2L11 chr1 237943724 237945275 - RNF181 chr2 85595725 85597708 + VMP1 chr17 59707192 59842255 + DDB1 chr11 61299451 61342596 - SAP18 chr13 21140514 21149084 + DOCK6 chr19 11199295 11262524 - NSMAF chr8 58583508 58659853 - APP chr21 25880550 26171128 - TMEM170A chr16 75443054 75465497 - TKFC chr11 61333210 61353295 + CTSZ chr20 58995185 59007254 - AL136454.1 chr1 192716132 192716653 + TPT1 chr13 45333471 45341370 - PTPN6 chr12 6946468 6961316 + CAPNS1 chr19 36139953 36150353 + CCNL2 chr1 1385711 1399335 - RABGAP1L chr1 174159410 174995308 + RACK1 chr5 181236897 181248096 - HMGN2 chr1 26472440 26476642 + SEZ6L2 chr16 29871159 29899547 - GAPDH chr12 6534512 6538374 + CD52 chr1 26317958 26320523 + PCBP2 chr12 53452102 53481162 + NDUFA11 chr19 5891276 5904006 - REXO1 chr19 1815248 1848483 - ZNF655 chr7 99558406 99576453 + DCAF12 chr9 34086387 34127399 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AC105942.1 chr1 94927361 94963616 + Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA