Entry Detail



General Information

Database ID:exR0263426
RNA Name:hsa-miR-663a
RNA Type:miRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):26208243End Site(bp):26208264
External Links:hsa-miR-663a



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE134266
Description:Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:Bone Metastatic Prostate Cancer
Case Sample:Bone Metastatic Prostate Cancer
Control Sample:Benign Prostatic Hyperplasia
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COL6A2
chr21
46098112
46132848
+
KLC2
chr11
66257294
66267860
+
REXO1
chr19
1815248
1848483
-
MIDN
chr19
1248553
1259140
+
STK35
chr20
2101827
2177038
+
MIGA2
chr9
129036621
129072082
+
SRPRA
chr11
126262938
126269144
-
KDM2A
chr11
67119263
67258082
+
JUNB
chr19
12791486
12793315
+
GNB1
chr1
1785285
1891117
-
SYVN1
chr11
65121780
65134533
-
SCN1B
chr19
35030470
35040449
+
SMAD3
chr15
67063763
67195169
+
HIF1AN
chr10
100529072
100559998
+
TNRC6A
chr16
24610209
24827632
+
ARHGAP1
chr11
46677080
46700619
-
ARL8A
chr1
202133404
202144743
-
PPDPF
chr20
63520765
63522206
+
KMT5A
chr12
123383773
123409353
+
RTL8A
chrX
135050932
135052196
-
SOX12
chr20
325595
330224
+
CYB5R3
chr22
42617840
42649392
-
PRR12
chr19
49591182
49626439
+
CAPN15
chr16
527712
554636
+
DMWD
chr19
45782947
45792845
-
BOC
chr3
113211003
113287459
+
FAM83H
chr8
143723933
143738234
-
CLSTN1
chr1
9728926
9823984
-
CALR
chr19
12938578
12944489
+
CMIP
chr16
81445170
81711762
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008738.7
chr19
33207129
33207639
+
AC020928.2
chr19
36773712
36775908
-
AC069281.2
chr7
100572232
100578700
-
AC234582.1
chr1
155195004
155205495
+
AL137127.1
chr1
19072110
19075511
-
AL355075.4
chr14
20343048
20343685
-
AL356488.2
chr1
109100193
109100619
+
GAS5
chr1
173858559
173868882
-
MIR663AHG
chr20
26167817
26251546
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG25
chr17
64145970
64146476
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE134266
Sample Source:Blood
Source Fraction:Extracellular Vesicle
Platform:GPL25134
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2519
Sample treatment protocol:The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA