exRNAdisease

Entry Detail

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General Information

Database ID: exR0263861 RNA Name: hsa-miR-769-5p RNA Type: miRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 46018961 End Site(bp): 46018982 External Links: hsa-miR-769-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACVR1B chr12 51951699 51997078 + ANGEL1 chr14 76786168 76826246 - ASB1 chr2 238426742 238452250 + BMPR2 chr2 202376327 202567751 + CAPNS1 chr19 36139953 36150353 + CBFB chr16 67028984 67101058 + CLDN11 chr3 170418865 170454733 + CLN8 chr8 1755778 1801711 + DBNDD1 chr16 90004871 90020128 - DCTN4 chr5 150708440 150759109 - EIF1AD chr11 65996545 66002176 - EIF1AX chrX 20124525 20141838 - FOXK1 chr7 4682295 4771442 + LONRF2 chr2 100271875 100322501 - MDM4 chr1 204516379 204558120 + MRTO4 chr1 19251805 19260128 + NUSAP1 chr15 41320794 41381050 + PLCD3 chr17 45108959 45133354 - PRKAA1 chr5 40759379 40798374 - PXN chr12 120210439 120265771 - RHPN1 chr8 143368876 143384221 + RUNX1 chr21 34787801 36004667 - TFAP4 chr16 4257186 4273075 - VAT1 chr17 43014607 43025123 - YPEL5 chr2 30146941 30160533 + ZDHHC9 chrX 129803288 129843909 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.4 chr15 82533175 82540008 - LINC00324 chr17 8220642 8224043 - MALAT1 chr11 65497688 65506516 + SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA