exRNAdisease

Entry Detail

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General Information

Database ID: exR0263937 RNA Name: hsa-miR-877-5p RNA Type: miRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 30584332 End Site(bp): 30584351 External Links: hsa-miR-877-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABR chr17 1003518 1229738 - DNAJB6 chr7 157335381 157417439 + EIF2AK1 chr7 6022247 6059175 - FOSL1 chr11 65892049 65900573 - IGF2BP1 chr17 48997385 49056145 + MAPK8IP2 chr22 50600793 50613981 + PHTF2 chr7 77798792 77957503 + PLD3 chr19 40348456 40380439 + SMG1 chr16 18804853 18926454 - TRAF7 chr16 2155698 2178129 + USP54 chr10 73497538 73625953 - ANAPC7 chr12 110372900 110403730 - EIF4ENIF1 chr22 31436977 31496108 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010442.1 chr5 466124 473098 - AC092718.4 chr16 81030770 81031485 + DNAAF4-CCPG1 chr15 55355248 55498360 - DSCAM-AS1 chr21 40383083 40385358 + LINC00910 chr17 43338741 43389199 - LINC01278 chrX 63222993 63561095 - NEAT1 chr11 65422774 65445540 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA